Transcription activation at Class II CAP‐dependent promoters
نویسندگان
چکیده
منابع مشابه
Transcription activation at class II CAP-dependent promoters.
Transcription activation at Class II CAP-dependent promoters provides a paradigm for understanding how a single activator molecule can make multiple interactions with the transcription machinery, with each interaction being responsible for a specific mechanistic consequence. At Class II CAP-dependent promoters, the DNA target site for CAP is centred near position -42, overlapping and replacing ...
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Class II CAP-dependent promoters, interacting with the RNAP ␣ subunit C-terminal domain (␣CTD) and facilitat-At Class I CAP-dependent promoters, interaction between the activating region and ␣CTD (and concomitant St. Louis, Missouri 63104 recruitment of RNAP to promoter DNA) appears to be the entire basis of transcription activation. Thus, at Class Summary I CAP-dependent promoters, removal of ...
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Nucleosome depletion at transcription start sites (TSS) has been documented genome-wide in multiple eukaryotic organisms. However, the mechanisms that mediate this nucleosome depletion and its functional impact on transcription remain largely unknown. We have studied these issues at human MHC class II (MHCII) genes. Activation-induced nucleosome free regions (NFR) encompassing the TSS were obse...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 1997
ISSN: 0950-382X,1365-2958
DOI: 10.1046/j.1365-2958.1997.2771641.x